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1

Malaria biology and disease pathogenesis: insights for new treatments

Miller, Louis H, Ackerman, Hans C, Su, Xin-zhuan, Wellems, Thomas E

Journal:

Nature Medicine

Year:

2013

Language:

english

File:

PDF, 1.60 MB

english, 2013

2

Plasmodium Genomics and Genetics: New Insights into Malaria Pathogenesis, Drug Resistance, Epidemiology, and Evolution

Su, Xin-zhuan, Lane, Kristin D., Xia, Lu, Sá, Juliana M., Wellems, Thomas E.

Journal:

Clinical Microbiology Reviews

Year:

2019

Language:

english

File:

PDF, 2.72 MB

english, 2019

3

Genetic linkage and association analyses for trait mapping in Plasmodium falciparum

Su, Xinzhuan, Hayton, Karen, Wellems, Thomas E.

Journal:

Nature Reviews Genetics

Year:

2007

Language:

english

File:

PDF, 1.09 MB

english, 2007

4

High frequency of PfCRT 76T in two Malian villages and its prevalence in severe relative to non-severe malaria

Mamadou Wélé, Abdoulaye A. Djimdé, Aldiouma Guindo, Abdoul H. Beavogui, Isaac Z. Traoré, Aboubacar Sadou, Dackouo Blaise, Dapa A. Diallo, Thomas E. Wellems, Ogobara K. Doumbo

Journal:

Year:

2011

Language:

english

File:

PDF, 139 KB

english, 2011

5

Homologous Genes Encode Two Distinct Histidine-Rich Proteins in a Cloned Isolate of Plasmodium falciparum

Thomas E. Wellems and Russell J. Howard

Journal:

Proceedings of the National Academy of Sciences

Year:

1986

Language:

english

File:

PDF, 911 KB

english, 1986

6

SPIE Proceedings [SPIE International Symposium on Optical Science and Technology - San Diego, CA (Sunday 29 July 2001)] Polarization Analysis and Measurement IV - Results of a new polarization simulation

Fetrow, Matthew P., Wellems, David, Sposato, Stephanie H., Bishop, Kenneth P., Caudill, Thomas R., Davis, Michael L., Simrell, Elizabeth R., Goldstein, Dennis H., Chenault, David B., Egan, Walter G.,

Year:

2002

Language:

english

File:

PDF, 402 KB

english, 2002

7

An evaluation of concurrent G6PD (A−) deficiency and sickle cell trait in Malian populations of children with severe or uncomplicated P. falciparum malaria

Aldiouma Guindo, Karim Traore, Seidina Diakite, Thomas E. Wellems, Ogobara K. Doumbo, Dapa Aly Diallo

Journal:

American Journal of Hematology

Year:

2011

Language:

english

File:

PDF, 774 KB

english, 2011

8

Non-opsonising aggregates of IgG and complement in haemoglobin C erythrocytes

Nathaniel J. Brittain, Cindy Erexson, Lawrence Faucette, Jerrold Ward, Hisashi Fujioka, Thomas E. Wellems, Rick M. Fairhurst

Journal:

British Journal of Haematology

Year:

2007

Language:

english

File:

PDF, 879 KB

english, 2007

9

Mutations in transmembrane domains 1, 4 and 9 of the Plasmodium falciparum chloroquine resistance transporter alter susceptibility to chloroquine, quinine and quinidine

Roland A. Cooper, Kristin D. Lane, Bingbing Deng, Jianbing Mu, Jigar J. Patel, Thomas E. Wellems, Xinzhuan Su, Michael T. Ferdig

Journal:

Molecular Microbiology

Year:

2007

Language:

english

File:

PDF, 499 KB

english, 2007

10

Mutations in transmembrane domains 1, 4 and 9 of the Plasmodium falciparum chloroquine resistance transporter alter susceptibility to chloroquine, quinine and quinidine

Roland A. Cooper, Kristin D. Lane, Bingbing Deng, Jianbing Mu, Jigar J. Patel, Thomas E. Wellems, Xinzhuan Su, Michael T. Ferdig

Journal:

Molecular Microbiology

Year:

2007

Language:

english

File:

PDF, 82 KB

english, 2007

11

Chloroquine resistance not linked to mdr-like genes in a Plasmodium falciparum cross

Wellems, Thomas E., Panton, Lindsey J., Gluzman, Ilya Y., do Rosario, Virgilio E., Gwadz, Robert W., Walker-Jonah, Annie, Krogstad, Donald J.

Journal:

Year:

1990

File:

PDF, 368 KB

1990

12

10.1038/35039531

Scherf, Artur, Freitas-Junior, Lúcio H., Bottius, Emmanuel, Pirrit, Lindsay A., Deitsch, Kirk W., Scheidig, Christine, Guinet, Francoise, Nehrbass, Ulf, Wellems, Thomas E.

Journal:

Year:

2000

Language:

english

File:

PDF, 295 KB

english, 2000

13

10.1038/35091151

Deitsch, Kirk W., Calderwood, Michael S., Wellems, Thomas E.

Journal:

Year:

2001

Language:

english

File:

PDF, 129 KB

english, 2001

14

10.1038/35091149

Deitsch, Kirk W., Calderwood, Michael S., Wellems, Thomas E.

Journal:

Year:

2001

Language:

english

File:

PDF, 105 KB

english, 2001

15

10.1038/35091146

Deitsch, Kirk W., Calderwood, Michael S., Wellems, Thomas E.

Journal:

Year:

2001

Language:

english

File:

PDF, 191 KB

english, 2001

16

How chloroquine works

Wellems, Thomas E.

Journal:

Year:

1992

File:

PDF, 281 KB

1992

17

Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum

Yuan, Jing, Johnson, Ronald L, Huang, Ruili, Wichterman, Jennifer, Jiang, Hongying, Hayton, Karen, Fidock, David A, Wellems, Thomas E, Inglese, James, Austin, Christopher P

Journal:

Nature Chemical Biology

Year:

2009

Language:

english

File:

PDF, 632 KB

english, 2009

18

Malaria-protective traits at odds in Africa?

Wellems, Thomas E, Fairhurst, Rick M

Journal:

Nature Genetics

Year:

2005

Language:

english

File:

PDF, 1.61 MB

english, 2005

19

Transporter of a malaria catastrophe

Wellems, Thomas E

Journal:

Nature Medicine

Year:

2004

Language:

english

File:

PDF, 493 KB

english, 2004

20

Mechanisms underlying mutually exclusive expression of virulence genes by malaria parasites

Dzikowski, Ron, Li, Felomena, Amulic, Borko, Eisberg, Andrew, Frank, Matthias, Patel, Suchit, Wellems, Thomas E, Deitsch, Kirk W

Journal:

Year:

2007

Language:

english

File:

PDF, 187 KB

english, 2007

21

Dissecting the loci of low-level quinine resistance in malaria parasites

Michael T. Ferdig, Roland A. Cooper, Jianbing Mu, Bingbing Deng, Deirdre A. Joy, Xin-zhuan Su, Thomas E. Wellems

Journal:

Molecular Microbiology

Year:

2004

Language:

english

File:

PDF, 279 KB

english, 2004

22

Plasmodium falciparum:Isolation of Large Numbers of Parasite Clones from Infected Blood Samples

Laura A. Kirkman, Xin-zhuan Su, Thomas E. Wellems

Journal:

Experimental Parasitology

Year:

1996

Language:

english

File:

PDF, 346 KB

english, 1996

23

Plasmodium falciparum:A High Proportion of Parasites from a Population of the Dd2 Strain Are Able to Invade Erythrocytes by an Alternative Pathway

Sandrine C. Soubes, Thomas E. Wellems, Louis H. Miller

Journal:

Experimental Parasitology

Year:

1997

Language:

english

File:

PDF, 58 KB

english, 1997

24

Plasmodium falciparum:A Rapid DNA Fingerprinting Method Using Microsatellite Sequences withinvarClusters

Xin-Zhuan Su, Thomas E. Wellems

Journal:

Experimental Parasitology

Year:

1997

Language:

english

File:

PDF, 230 KB

english, 1997

25

Plasmodium falciparum:Parasite Typing by Using a Multicopy Microsatellite Marker, PfRRM

Xin-Zhuan Su, Daniel J. Carucci, Thomas E. Wellems

Journal:

Experimental Parasitology

Year:

1998

Language:

english

File:

PDF, 183 KB

english, 1998

26

Plasmodium falciparum:Assignment of Microsatellite Markers to Chromosomes by PFG–PCR

Xin-zhuan Su, Thomas E. Wellems

Journal:

Experimental Parasitology

Year:

1999

Language:

english

File:

PDF, 43 KB

english, 1999

27

Structure and expression of the knob-associated histidine-rich protein of Plasmodium falciparum

Joan Ellis, David O. Irving, Thomas E. Wellems, Russell J. Howard, George A.M. Cross

Journal:

Molecular and Biochemical Parasitology

Year:

1987

Language:

english

File:

PDF, 1.10 MB

english, 1987

28

Purification and partial characterization of an unusual protein of Plasmodium falciparum: histidine-rich protein II

Lindsey J. Panton, Peter McPhie, W. Lee Maloy, Thomas E. Wellems, Diane W. Taylor, Russell J. Howard

Journal:

Molecular and Biochemical Parasitology

Year:

1989

Language:

english

File:

PDF, 1.14 MB

english, 1989

29

An RFLP map of the Plasmodium falciparum genome, recombination rates and favored linkage groups in a genetic cross

Annie Walker-Jonah, Stephen A. Dolan, Robert W. Gwadz, Lindsey J. Panton, Thomas E. Wellems

Journal:

Molecular and Biochemical Parasitology

Year:

1992

Language:

english

File:

PDF, 582 KB

english, 1992

30

Identification of a Plasmodium falciparum histone 2A gene

Kathleen A. Creedon, David C. Kaslow, Pradipsinh K. Rathod, Thomas E. Wellems

Journal:

Molecular and Biochemical Parasitology

Year:

1992

Language:

english

File:

PDF, 192 KB

english, 1992

31

Restriction polymorphisms and fingerprint patterns from an interspersed repetitive element of Plasmodium falciparum DNA

Stephen A. Dolan, Jacqueline A. Herrfeldt, Thomas E. Wellems

Journal:

Molecular and Biochemical Parasitology

Year:

1993

Language:

english

File:

PDF, 734 KB

english, 1993

32

A genetic locus on Plasmodium falciparum chromosome 12 linked to a defect in mosquito-infectivity and male gametogenesis

Akhil B. Vaidya, Olga Muratova, Françoise Guinet, David Keister, Thomas E. Wellems, David C. Kaslow

Journal:

Molecular and Biochemical Parasitology

Year:

1995

Language:

english

File:

PDF, 634 KB

english, 1995

33

Glycophorin B as an EBA-175 independent Plasmodium falciparum receptor of human erythrocytes

Stephen A. Dolan, Jo Lynn Proctor, David W. Alling, Yasuto Okubo, Thomas E. Wellems, Louis H. Miller

Journal:

Molecular and Biochemical Parasitology

Year:

1994

Language:

english

File:

PDF, 948 KB

english, 1994

34

Membrane modifications in erythrocytes parasitized by Plasmodium falciparum

Kirk W. Deitsch, Thomas E. Wellems

Journal:

Molecular and Biochemical Parasitology

Year:

1996

Language:

english

File:

PDF, 1.17 MB

english, 1996

35

Plasmodium vivax: allele variants of the mdr1 gene do not associate with chloroquine resistance among isolates from Brazil, Papua, and monkey-adapted strains

Juliana Martha Sá, Takashi Nomura, Joana d’Arc Neves, J. Kevin Baird, Thomas E. Wellems, Hernando A. del Portillo

Journal:

Experimental Parasitology

Year:

2005

Language:

english

File:

PDF, 1.01 MB

english, 2005

36

PfCG2, a Plasmodium falciparum protein peripherally associated with the parasitophorous vacuolar membrane, is expressed in the period of maximum hemoglobin uptake and digestion by trophozoites

Roland A. Cooper, Janni Papakrivos, Kristin D. Lane, Hisashi Fujioka, Klaus Lingelbach, Thomas E. Wellems

Journal:

Molecular and Biochemical Parasitology

Year:

2005

Language:

english

File:

PDF, 759 KB

english, 2005

37

Expression and function of pvcrt-o, a Plasmodium vivax ortholog of pfcrt, in Plasmodium falciparum and Dictyostelium discoideum

Juliana Martha Sá, Marcio M. Yamamoto, Carmen Fernandez-Becerra, Mauro Ferreira de Azevedo, Janni Papakrivos, Bronwen Naudé, Thomas E. Wellems, Hernando A. del Portillo

Journal:

Molecular and Biochemical Parasitology

Year:

2006

Language:

english

File:

PDF, 637 KB

english, 2006

38

Probing the multifactorial basis of Plasmodium falciparum quinine resistance: Evidence for a strain-specific contribution of the sodium-proton exchanger PfNHE

Louis J. Nkrumah, Paul M. Riegelhaupt, Pedro Moura, David J. Johnson, Jigar Patel, Karen Hayton, Michael T. Ferdig, Thomas E. Wellems, Myles H. Akabas, David A. Fidock

Journal:

Molecular and Biochemical Parasitology

Year:

2009

Language:

english

File:

PDF, 803 KB

english, 2009

39

Allelic modifications of the cg2 and cg1 genes do not alter the chloroquine response of drug-resistant Plasmodium falciparum

David A Fidock, Takashi Nomura, Roland A Cooper, Xin-zhuan Su, Angela K Talley, Thomas E Wellems

Journal:

Molecular and Biochemical Parasitology

Year:

2000

Language:

english

File:

PDF, 166 KB

english, 2000

40

Rapid recombination among transfected plasmids, chimeric episome formation and trans gene expression in Plasmodium falciparum

Madhusudan Kadekoppala, Paul Cheresh, Drew Catron, Dar-der Ji, Kirk Deitsch, Thomas E. Wellems, H.S. Seifert, Kasturi Haldar

Journal:

Molecular and Biochemical Parasitology

Year:

2001

Language:

english

File:

PDF, 270 KB

english, 2001

41

Physical mapping of a defect in Plasmodium falciparum male gametocytogenesis to an 800 kb segment of chromosome 12

Françoise Guinet, Thomas E Wellems

Journal:

Molecular and Biochemical Parasitology

Year:

1997

Language:

english

File:

PDF, 70 KB

english, 1997

42

Intra-cluster recombination and var transcription switches in the antigenic variation of Plasmodium falciparum

Kirk W. Deitsch, Amy del Pinal, Thomas E. Wellems

Journal:

Molecular and Biochemical Parasitology

Year:

1999

Language:

english

File:

PDF, 267 KB

english, 1999

43

EBL-1, a putative erythrocyte binding protein of Plasmodium falciparum, maps within a favored linkage group in two genetic crosses

David S Peterson, Thomas E Wellems

Journal:

Molecular and Biochemical Parasitology

Year:

2000

Language:

english

File:

PDF, 360 KB

english, 2000

44

The Giardia lamblia trophozoite contains sets of closely related chromosomes

Adam, Rodney D., Nash, Theodore E., Wellems, Thomas E.

Journal:

Nucleic Acids Research

Year:

1988

Language:

english

File:

PDF, 3.06 MB

english, 1988

45

Toward a High-ResolutionPlasmodium falciparumLinkage Map: Polymorphic Markers from Hundreds of Simple Sequence Repeats

Xin-zhuan Su, Thomas E. Wellems

Journal:

Year:

1996

Language:

english

File:

PDF, 524 KB

english, 1996

46

Energy dependence of chloroquine accumulation and chloroquine efflux in Plasmodium falciparum

Donald J. Krogstad, Ilya Y. Gluzman, Barbara L. Herwaldt, Paul H. Schlesinger, Thomas E. Wellems

Journal:

Biochemical Pharmacology

Year:

1992

Language:

english

File:

PDF, 564 KB

english, 1992

47

Plasmodium falciparum: Rapid detection of dihydrofolate reductase mutations that confer resistance to cycloguanil and pyrimethamine

Frederick N. Gyang, David S. Peterson, Thomas E. Wellems

Journal:

Experimental Parasitology

Year:

1992

Language:

english

File:

PDF, 550 KB

english, 1992

48

Sequence, transcript characterization and polymorphisms of a Plasmodium falciparum gene belonging to the heat-shock protein (HSP) 90 family

Xin-zhuan Su, Thomas E. Wellems

Journal:

Year:

1994

Language:

english

File:

PDF, 942 KB

english, 1994

49

A comparison of anemia in hemoglobin C and normal hemoglobin A children with Plasmodium falciparum malaria

Dapa A Diallo, Ogobara K Doumbo, Alassane Dicko, Aldiouma Guindo, Drissa Coulibaly, Kassoum Kayentao, Abdoulaye A Djimdé, Mahamadou A Théra, Rick M Fairhurst, Christopher V Plowe, Thomas E Wellems

Journal:

Year:

2004

Language:

english

File:

PDF, 63 KB

english, 2004

50

Hemoglobin C modulates the surface topography of Plasmodium falciparum-infected erythrocytes

Takayuki Arie, Rick M. Fairhurst, Nathaniel J. Brittain, Thomas E. Wellems, James A. Dvorak

Journal:

Journal of Structural Biology

Year:

2005

Language:

english

File:

PDF, 784 KB

english, 2005

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